The CTD² Network and Cancer Systems Biology Consortium organized a virtual symposium series titled “Multidisciplinary Approaches to Understand Cancer Treatment Resistance”. Please join us on 11/16, 11/17, 12/2, 12/16, and 12/17. Click here to view the registration website.
Publications
644 Publications Available
Nature Medicine
In this reveiw authors discuss how organoid methods have the potential to herald the dawn of a new era in cancer biology investigation.
Cancer Cell
Researchers conducted a large-scale functional genetic study to characterize mechanisms of resistance to ALK inhibition in ALK-dependent lung cancer cells and identified additional members of known of putative resistance drivers.
PLoS One
The Journal of Clinical Endocrinology & Metabolism
Authors find a previously unknown mutant fusion of RET tyrosine kinase in a case of medullary thyroid carcinoma.
Molecular Cancer Research
Researchers identify FRS2 as an oncogene in a subset of high-grade serous ovarian cancers.
Blood
Combination therapy of ruxolitinib and dasatinib extends survival and prevents relapse of a mouse model of Ph+ ALL.
Nature
Researchers discuss parallel genetic evolution of separate metastatic sites with different PTEN genomic alterations leads to a convergent PTEN-null phenotype resistant to PI(3)Kα inhibition
Cancer Cell
Investigators identify the role of GATA2 in chemotherapy resistance in prostate cancer.
Genome Biology
Cancer Discovery
Researchers generate a systematic and quantitative chemical-genetic interaction map that measures the influence of 51 aberrant cancer genes on 90 drug responses.