The CTD² Network and Cancer Systems Biology Consortium organized a virtual symposium series titled “Multidisciplinary Approaches to Understand Cancer Treatment Resistance”. Please join us on 11/16, 11/17, 12/2, 12/16, and 12/17. Click here to view the registration website.
Publications
644 Publications Available
Proceedings of the Pacific Symposium on Biocomputing 2016
The authors incorporated existing knowledge of gene interactions to generate more accurate statistical predictions of gene interaction networks.
Molecular Cancer Research
An shRNA screen identified the only lung cancer cell line in the panel to be sensitive to knockdown of MAP2K1 and thus sensitive to MEK1 inhibition.
Nature Chemical Biology
Expression of cytochrome P450 makes cell lines sensitive to oxalamides and benzothiazoles.
Nature Chemical Biology
These results implicate PDE3A modulators as candidate cancer therapeutic agents and demonstrate the power of predictive chemogenomics in small-molecule discovery.
Scientific Reports
Researchers describe methodology for detailed studies of human Neural crest cells (NCC), and clarifies roles for retinoids and bone morphogenetic proteins in the differentiation of human pluripotent stem cells to trunk NCC and to sympathoadrenal lineages.
Nature Communications
The authors use a gain-of-function screening platform to clone and functionally assess mutations that occur at low frequency in pancreatic cancer
Bioinformatics
Investigators develop an algorithm to statistically analyze off-target effects of RNAi and CRISPR screens.
Nature
Research shows that extrinsic factors have a larger influence on cancer risk than intrinsic factors
Cold Spring Harbor Symposia on Quantitative Biology
Cold Spring Harbor symposia on quantitative biology