Publications
Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.
* denotes publications from the CTD2 initiative that are results of intra-Network collaborations
Research shows that extrinsic factors have a larger influence on cancer risk than intrinsic factors
The transcription factor SOX4 plays a critical role in prostate cancer and may be a potential target for combinatorial therapies.
Review on potential applications of the pancreatic ductal organoids(PDA), three-dimensional culture systems and organoid-based xenografts as new preclinical models for PDA.
Scientists studied the DNA variant in the LMO1 gene which leads to neuroblastoma development.
Researchers highlight Myc in inducing glutamine synthesis and suggest a molecular connection between DNA demethylation and glutamine metabolism in Myc-driven cancers.
This study demonstrates overexpression of YAP stimulates cell proliferation whereas knocking down YAP or treating cells with Verteporfin inhibited cell proliferation. This study provides potential approaches to select patients likely to benefit from Verteporfin.
Researchers use the Cancer Therapeutics Response Portal to analyze mechanism of action for small molecules based on changes in gene expression.