Publications
Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.
* denotes publications from the CTD2 initiative that are results of intra-Network collaborations
Researchers screened a panel of non-small cell lung cancer cell lines for chemical sensitivity and identified SW044248, a topoisomerase I inhibitor.
Researchers demonstrate that SWI/SNF-mutant cancer cells are primarily dependent on a non-catalytic role of EZH2 in the stabilization of the PRC2 complex, and that they are only partially dependent on EZH2 histone methyltransferase activity.
Epigenetic regulator RNF2 has a dual role in tumorigenesis and metastasis of melanomas.
Researchers discovered mutations in the MLLT1 gene in Wilms tumor that might help explain Wilms tumor development.
Investigators used large-scale genomics to separate driver and passenger mutations and learn more about the functionality of driver mutations.
Researchers compared whole-exome sequencing of matched benign, malignant and metastatic skin tumors to study the evolution of metastasis.
Researchers used bioinformatics tools to detect heterogeneity within tumors in The Cancer Genome Atlas.
The authors developed a web interface to allow the linkage of genetic information from The Cancer Genome Atlas with associated clinical data.
The researchers used an algorithm to identify drivers of the transformation from follicular lymphoma to diffuse large B-cell lymphoma
Researchers created a high-throughput method for identifying protein-protein interactions in live cells