The CTD² Network and Cancer Systems Biology Consortium organized a virtual symposium series titled “Multidisciplinary Approaches to Understand Cancer Treatment Resistance”. Please join us on 11/16, 11/17, 12/2, 12/16, and 12/17. Click here to view the registration website.
Publications
644 Publications Available
Oncogene
Researchers review the splicing landscape of TP53, BARD1 and AR to illuminate roles for alternative splicing in cancer. We also examine the intersection between alternative splicing pathways and novel therapeutic approaches.
Proceedings of the Pacific Symposium on Biocomputing 2014
Investigators evaluated over 110,000 algorithms for predicting compound sensitivity, and provide modeling guidelines.
Proceedings of the Pacific Symposium on Biocomputing 2014
The authors propose a novel Bayesian inference method for fitting ridge-regression.
Advances in Cancer Research
Researchers discuss the etiology of oligodendrocyte progenitor cells-derived gliomas and reveal new therapeutic avenues.
Molecular Cancer Therapy
The results suggest that AURK inhibition subsequent to radiation,may enhance the efficacy of radiotherapy in human glioblastomas.
Cancer Research
Vitamin D receptor agonists may show enhanced efficacy in p53-negative lung cancer patients.
Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery
Trends in Genetics
The authors provide an overview of the evolution of phenotypic small-molecule profiling and discuss the most significant and recent profiling efforts.
BMC Genomics
Researchers present a novel method for Cancer Module Discovery, CaMoDi, and demonstrate through extensive simulations on the TCGA Pan-Cancer dataset.
Oncogene
Researchers investigated GATA6-regulated genes to identify targets for drug therapy for GATA6-overexpressing gastric cancers.
Nature Biotechnology
To identify possible drug combinations the DREAM consortium initiated a challenge to rank the synergy of 91 compound pairs.