How to access multiple datasets

The CTD² Network and Cancer Systems Biology Consortium organized a virtual symposium series titled “Multidisciplinary Approaches to Understand Cancer Treatment Resistance”. Please join us on 11/16, 11/17, 12/2, 12/16, and 12/17. Click here to view the registration website.

Publications

644 Publications Available

Genomic data imputation with variational auto-encoders

Gigascience
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Organotypic culture assays for murine and human primary and metastatic-site tumors

Nat Protoc.
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Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening*

J Mol Cell Biol.
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Organoid Models of Tumor Immunology.

Trends Immunol.
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Tissue- and development-stage-specific mRNA and heterogeneous CNV signatures of human ribosomal proteins in normal and cancer samples

Nucleic Acids Res.
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Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma

Nature Communications
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The Cancer Dependency Map enables drug mechanism-of-action investigations.

Mol Syst Biol.
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Systems approach to rational combination therapy: PARP inhibitors

Biochem Soc Trans.
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Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms

Blood

Study highlights the usage of FDA-approved tyrosine kinase inhibitors for treating leukemia patients with neurotrophic receptor tyrosine kinase mutations.

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Discovery of a selective inhibitor of doublecortin like kinase 1.

Nature Chemical Biology

Integrated analysis of RNA-sequencing, proteomics, and phosphoproteomics data indicate doublecortin like kinase 1 (DCLK1) modulates proteins and pathways associated with cell motility in patient-derived pancreatic ductal adenocarcinoma (PDAC) organoids.

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