Publications

Scientists at DFCI demonstrated that binding of transcription factor, ERG, to chromatin remodeling complex, BAF, is essential to facilitate basal-to-luminal transition, a hallmark of prostate oncogenesis.

Researchers at UCSF developed an analytical framework for constructing a human genetic interaction map, a powerful tool to identify genetic interactions between genes and suggest new combination therapies for cancer.

In vivo gain-of-function genetic screen identifies TMEMB, a transmembrane protein as a novel driver of invasion and metastasis in lung cancer.

In vivo functional screening identifies transcriptional repressor, GATAD2B, as a potent driver of tumor growth and metastasis in KRAS-mutant lung cancer through interaction with c-Myc.