Publications
Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.
* denotes publications from the CTD2 initiative that are results of intra-Network collaborations
Investigators evaluated over 110,000 algorithms for predicting compound sensitivity, and provide modeling guidelines.
The authors propose a novel Bayesian inference method for fitting ridge-regression.
Researchers discuss the etiology of oligodendrocyte progenitor cells-derived gliomas and reveal new therapeutic avenues.
The results suggest that AURK inhibition subsequent to radiation,may enhance the efficacy of radiotherapy in human glioblastomas.
Vitamin D receptor agonists may show enhanced efficacy in p53-negative lung cancer patients.
The authors provide an overview of the evolution of phenotypic small-molecule profiling and discuss the most significant and recent profiling efforts.
Researchers present a novel method for Cancer Module Discovery, CaMoDi, and demonstrate through extensive simulations on the TCGA Pan-Cancer dataset.
Researchers investigated GATA6-regulated genes to identify targets for drug therapy for GATA6-overexpressing gastric cancers.
To identify possible drug combinations the DREAM consortium initiated a challenge to rank the synergy of 91 compound pairs.
This is an editorial comment on "Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer" published in J Natl Cancer Inst